mouse APLP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Aplp1.
shAAV-252824
AAV-m-APLP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Aplp1 (amyloid beta (A4) precursor-like protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
APLP1 may play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I|Function: The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis (By similarity).
Gene ID
11803
Gene Name (Vector)
amyloid beta (A4) precursor-like protein 1
Gene Symbol
Aplp1
ORF Size (aa)
1965
ORF Size (bp)
1965 bp
RefSeq ID
NM_007467
RefSeq Synonyms
NM_007467, BC021877,
Species
mouse
UniGene ID
Mm.2381
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.