mouse APLP1 shRNA silencing AAV

Cat. No: shAAV-252824

Availability: 4-5 weeks

Name: AAV-m-APLP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Aplp1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Aplp1
Gene Name: amyloid beta (A4) precursor-like protein 1
Gene ID: 11803
ORF Size: 1965 bp
RefSeq#: NM_007467
Gene Description: APLP1 may play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I|Function: The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis (By similarity).
UniGene ID: Mm.2381