mouse AP3B2 shRNA silencing AAV

Name 
AAV-m-AP3B2-shRNA
Cat No 
shAAV-252776
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ap3b2.

shAAV-252776
AAV-m-AP3B2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ap3b2 (adaptor-related protein complex 3, beta 2 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI549966; AU042881; beta-NAP; beta3B; Naptb; [b]-NAP
Description (Vector)
Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles.
Gene ID
11775
Gene Name (Vector)
adaptor-related protein complex 3, beta 2 subunit
Gene Symbol
Ap3b2
ORF Size (aa)
3249
ORF Size (bp)
3249 bp
RefSeq ID
NM_021492
RefSeq Synonyms
NM_021492, BC139379, BC139378,
Species
mouse
UniGene ID
Mm.322894

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.