mouse ANK1 shRNA silencing AAV

Name
AAV-m-ANK1-shRNA

Cat No
shAAV-252627

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Ank1.

shAAV-252627

AAV-m-ANK1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ank1 (ankyrin 1, erythroid). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ank-1; nb; pale

Description (Vector)

Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions|Function: Isoform Mu17 together with obscurin in skeletal muscle may provide a molecular link between the sarcoplasmic reticulum and myofibrils.

Gene ID

11733

Gene Name (Vector)

ankyrin 1, erythroid

Gene Symbol

Ank1

ORF Size (aa)

5559

ORF Size (bp)

5559 bp

RefSeq ID

NM_031158

RefSeq Synonyms

NM_031158, NM_001310437, NM_001310436, NM_001277289, NM_001277286, NM_001277284, NM_001277281, NM_001277280, NM_001110783, BC171944, BC138029, BC079910,

Species

mouse

UniGene ID

Mm.476804

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.