mouse ALKBH2 shRNA silencing AAV

Name 
AAV-m-ALKBH2-shRNA
Cat No 
shAAV-252514
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Alkbh2.

shAAV-252514
AAV-m-ALKBH2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Alkbh2 (alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9530023G02; Abh2; AU016977; mABH2
Description (Vector)
Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
Gene ID
231642
Gene Name (Vector)
alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
Gene Symbol
Alkbh2
ORF Size (aa)
720
ORF Size (bp)
720 bp
RefSeq ID
NM_175016
RefSeq Synonyms
NM_175016, BC062188,
Species
mouse
UniGene ID
Mm.332593

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.