mouse ADRA2A shRNA silencing AAV

Name 
AAV-m-ADRA2A-shRNA
Cat No 
shAAV-252167
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Adra2a.

shAAV-252167
AAV-m-ADRA2A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Adra2a (adrenergic receptor, alpha 2a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Adra-2; Adra-2a; alpha(2A)AR; alpha2-C10; alpha2A; alpha2A-AR; AW122659
Description (Vector)
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.
Gene ID
11551
Gene Name (Vector)
adrenergic receptor, alpha 2a
Gene Symbol
Adra2a
ORF Size (aa)
1398
ORF Size (bp)
1398 bp
RefSeq ID
NM_007417
RefSeq Synonyms
NM_007417, BC138531,
Species
mouse
UniGene ID
Mm.235195

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.