mouse RGNEF shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Arhgef28.
shAAV-251095
AAV-m-RGNEF-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Arhgef28 (Rho guanine nucleotide exchange factor (GEF) 28). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9230110L08Rik; AI323540; D13Bwg1089e; p190RhoGEF; Rgnef; RhoGEF; Rhoip2; RIP2
Description (Vector)
Functions as a RHOA-specific guanine nucleotide exchange factor regulating signaling pathways downstream of integrins and growth factor receptors. Functions in axonal branching, synapse formation and dendritic morphogenesis. Functions also in focal adhesion formation, cell motility and B-lymphocytes activation. May regulate NEFL expression and aggregation and play a role in apoptosis (By similarity).
Gene ID
110596
Gene Name (Vector)
Rho guanine nucleotide exchange factor (GEF) 28
Gene Symbol
Arhgef28
ORF Size (aa)
5103
ORF Size (bp)
5103 bp
RefSeq ID
NM_012026
RefSeq Synonyms
NM_012026, BC138030,
Species
mouse
UniGene ID
Mm.252718
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.