mouse 2610301G19RIK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ccar2.
shAAV-250817
AAV-m-2610301G19RIK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ccar2 (cell cycle activator and apoptosis regulator 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610301G19Rik; Dbc1; mKIAA1967
Description (Vector)
Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.
Gene ID
219158
Gene Name (Vector)
cell cycle activator and apoptosis regulator 2
Gene Symbol
Ccar2
ORF Size (aa)
2769
ORF Size (bp)
2769 bp
RefSeq ID
NM_146055
RefSeq Synonyms
NM_146055, BC038346, BC021475,
Species
mouse
UniGene ID
Mm.218284
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.