mouse FTSJD2 shRNA silencing AAV

Name 
AAV-m-FTSJD2-shRNA
Cat No 
shAAV-250199
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cmtr1.

shAAV-250199
AAV-m-FTSJD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cmtr1 (cap methyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1300018I05Rik; AI451264; Ftsjd2; MTr1
Description (Vector)
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1). Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
Gene ID
74157
Gene Name (Vector)
cap methyltransferase 1
Gene Symbol
Cmtr1
ORF Size (aa)
2514
ORF Size (bp)
2514 bp
RefSeq ID
NM_028791
RefSeq Synonyms
NM_028791, BC024691,
Species
mouse
UniGene ID
Mm.475060

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.