mouse 1110034B05RIK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse TYW5.
shAAV-250146
AAV-m-1110034B05RIK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse TYW5 (tRNA-yW synthesizing protein 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110034B05Rik
Description (Vector)
tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.
Gene ID
68736
Gene Name (Vector)
tRNA-yW synthesizing protein 5
Gene Symbol
TYW5
ORF Size (aa)
948
RefSeq ID
NM_001037742
RefSeq Synonyms
NM_001302964, NM_001302963, NM_001302962, NM_001114102, NM_001037742, BC132289,
Species
mouse
UniGene ID
Mm.288490
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.