mouse FBXO31 shRNA silencing AAV

Name 
AAV-m-FBXO31-shRNA
Cat No 
shAAV-250106
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Fbxo31.

shAAV-250106
AAV-m-FBXO31-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fbxo31 (F-box protein 31). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110003O08Rik; 2310046N15Rik; Fbx14; Fbxo14
Description (Vector)
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor.
Gene ID
76454
Gene Name (Vector)
F-box protein 31
Gene Symbol
Fbxo31
ORF Size (aa)
1050
ORF Size (bp)
1050 bp
RefSeq ID
NM_133765
RefSeq Synonyms
NM_133765, BC026929,
Species
mouse
UniGene ID
Mm.24829

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.