human PRPF40A shRNA silencing AAV

Name 
AAV-h-PRPF40A-shRNA
Cat No 
shAAV-234450
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PRPF40A.

shAAV-234450
AAV-h-PRPF40A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRPF40A (pre-mRNA processing factor 40 homolog A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
fas ligand-associated factor 1; Fas-ligand associated factor 1; FBP11; FBP-11; FLAF1; FNBP3; formin binding protein 3; formin-binding protein 11; Formin-binding protein 3; HIP10; HIP-10; huntingtin yeast partner A; huntingtin-interacting protein 10; Huntingtin-interacting protein A; HYPA; NY-REN-6; NY-REN-6 antigen; pre-mRNA-processing factor 40 homolog A; Prp40; PRP40 pre-mRNA processing factor 40 homolog A; renal carcinoma antigen NY-REN-6
Description (eCommerce)
Formin-binding protein 11 (FBP11) binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). FBP11 plays a role in the regulation of cell morphology and cytoskeletal organization. It is required in the control of cell shape and migration. It may play a role in cytokinesis and pre-mRNA splicing [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75400].
Gene ID
55660
Gene Name (eCommerce)
pre-mRNA processing factor 40 homolog A
Gene Name (Vector)
pre-mRNA processing factor 40 homolog A
Gene Symbol
PRPF40A
HGNC ID
HGNC:16463
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
649
ORF Size (bp)
649 bp
Protein Name (eCommerce)
Pre-mRNA-processing factor 40 homolog A
RefSeq ID
NM_017892
RefSeq Synonyms
NM_017892, BC027178,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Gene Expression,Immunology,mRNA Processing,mRNA Splicing,RNA Processing
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,immunology,genetics
Species
human
Target Sentence
Formin-binding protein 11 (FBP11) binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). FBP11 plays a role in the regulation of cell morphology and cytoskeletal organization. It is required in the control of cell shape and migration. It may play a role in cytokinesis and pre-mRNA splicing [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75400].
UniProt ID (eCommerce)
O75400

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.