human DOCK10 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DOCK10.
shAAV-234415
AAV-h-DOCK10-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DOCK10 (dedicator of cytokinesis 10). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
dedicator of cytokinesis protein 10; dopamine receptor interacting protein 2; DRIP2; Nbla10300; ZIZ3; zizimin3; Zizimin-3
Description (eCommerce)
DOCK10 is a potential Rho-guanine nucleotide exchange factor (Rho-GEF) that may function to activate small GTPases such as Rac and Cdc42. It is a member of the CZH (CDM-zizimin homology) family of proteins that contain two highly conserved domains, CZH1 and CZH2.
Gene ID
55619
Gene Name (eCommerce)
dedicator of cytokinesis 10
Gene Name (Vector)
dedicator of cytokinesis 10
Gene Symbol
DOCK10
HGNC ID
HGNC:23479
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1629
ORF Size (bp)
1629 bp
Protein Name (eCommerce)
Dedicator of cytokinesis protein 10
RefSeq ID
NM_014689
RefSeq Synonyms
NM_014689, NM_001290263, BC015018,
Research Areas
Cell Cycle,Cell Division
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
DOCK10 is a potential Rho-guanine nucleotide exchange factor (Rho-GEF) that may function to activate small GTPases such as Rac and Cdc42. It is a member of the CZH (CDM-zizimin homology) family of proteins that contain two highly conserved domains, CZH1 and CZH2.
UniProt ID (eCommerce)
Q96BY6
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.