human TAC4 shRNA silencing AAV

Name
AAV-h-TAC4-shRNA

Cat No
shAAV-234067

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TAC4.

shAAV-234067

AAV-h-TAC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TAC4 (tachykinin 4 (hemokinin)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EK; HK-1; HK1; PPT-C

Description (Vector)

TAC4 is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

255061

Gene Name (Vector)

tachykinin 4 (hemokinin)

Gene Symbol

TAC4

HGNC ID

HGNC:16641

ORF Size (aa)

342

RefSeq ID

NM_001077503

RefSeq Synonyms

NM_170685, NM_001077506, NM_001077505, NM_001077504, NM_001077503, BC111858,

Species

human

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.