human MAP3K6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MAP3K6.
shAAV-233277
AAV-h-MAP3K6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MAP3K6 (mitogen-activated protein kinase kinase kinase 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ASK2; MAPKKK6; MEKK6
Description (Vector)
MAP3K6 encodes a member of the serine/threonine protein kinase family. The encoded kinase was identified by its interaction with MAP3K5/ASK, a protein kinase and an activator of c-Jun kinase (MAPK7/JNK) and MAPK14/p38 kinase. This kinase was found to weakly activate MAPK7, but not MAPK1/ERK or MAPK14. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.
Gene ID
9064
Gene Name (Vector)
mitogen-activated protein kinase kinase kinase 6
Gene Symbol
MAP3K6
HGNC ID
HGNC:6858
ORF Size (aa)
2396
ORF Size (bp)
2396 bp
RefSeq ID
NM_004672
RefSeq Synonyms
NM_004672, NM_001297609, BC015914,
Species
human
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.