human CCT5 shRNA silencing AAV

Name 
AAV-h-CCT5-shRNA
Cat No 
shAAV-230713
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CCT5.

shAAV-230713
AAV-h-CCT5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CCT5 (chaperonin containing TCP1 subunit 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CCTE; CCT-epsilon; chaperonin containing TCP1, subunit 5 (epsilon); epididymis secretory protein Li 69; HEL-S-69; PNAS-102; T-complex protein 1 subunit epsilon; TCP-1-epsilon
Description (eCommerce)
Chaperonin containing TCP1, subunit 5 (epsilon) (CCT5) is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin [taken from NCBI Entrez Gene (Gene ID: 22948)].
Description (Vector)
CCT5 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. In addition, three pseudogenes of this gene have been identified.
Gene ID
22948
Gene Name (eCommerce)
chaperonin containing TCP1 subunit 5
Gene Name (Vector)
chaperonin containing TCP1 subunit 5
Gene Symbol
CCT5
HGNC ID
HGNC:1618
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1626
ORF Size (bp)
1626 bp
Protein Name (eCommerce)
T-complex protein 1 subunit epsilon
RefSeq ID
NM_012073
RefSeq Synonyms
NM_012073, NM_001306156, NM_001306155, NM_001306154, NM_001306153, BC035499, BC006543,
Research Areas
Cytoskeleton,Host-Virus Interactions,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,Protein Folding,Response to Virus,Translational Control
Research Areas (Faceted)
cell_biology,developmental_biology,immunology,infectious_disease,metabolism,neurobiology,transcription_translation
Species
human
Target Sentence
Chaperonin containing TCP1, subunit 5 (epsilon) (CCT5) is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin [taken from NCBI Entrez Gene (Gene ID: 22948)].
UniGene ID
Hs.1600
UniProt ID (eCommerce)
P48643

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.