human HPGD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HPGD.
shAAV-230151
AAV-h-HPGD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HPGD (hydroxyprostaglandin dehydrogenase 15-(NAD)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1
Description (Vector)
HPGD encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
3248
Gene Name (Vector)
hydroxyprostaglandin dehydrogenase 15-(NAD)
Gene Symbol
HPGD
HGNC ID
HGNC:5154
ORF Size (aa)
801
ORF Size (bp)
801 bp
RefSeq ID
NM_000860
RefSeq Synonyms
NM_001256307, NM_001256306, NM_001256305, NM_001256301, NM_001145816, NM_000860, BC018986,
Species
human
UniGene ID
Hs.596913
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.