human YES1 shRNA silencing AAV

Name 
AAV-h-YES1-shRNA
Cat No 
shAAV-227964
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human YES1.

shAAV-227964
AAV-h-YES1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human YES1 (YES proto-oncogene 1, Src family tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
c-yes; HsT441; P61-YES; Yes
Description (Vector)
YES1 is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. YES1 lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.
Gene ID
7525
Gene Name (Vector)
YES proto-oncogene 1, Src family tyrosine kinase
Gene Symbol
YES1
HGNC ID
HGNC:12841
ORF Size (aa)
1632
ORF Size (bp)
1632 bp
RefSeq ID
NM_005433
RefSeq Synonyms
NM_005433, BC048960,
Species
human
UniGene ID
Hs.194148

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.