human XPNPEP3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human XPNPEP3.
shAAV-227912
AAV-h-XPNPEP3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human XPNPEP3 (X-prolyl aminopeptidase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APP3; ICP55; NPHPL1
Description (Vector)
XPNPEP3 belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.
Gene ID
63929
Gene Name (Vector)
X-prolyl aminopeptidase 3
Gene Symbol
XPNPEP3
HGNC ID
HGNC:28052
ORF Size (aa)
837
RefSeq ID
NM_022098
RefSeq Synonyms
NM_022098, NM_001204827, BC004989, BC001681, BC001208,
Species
human
UniGene ID
Hs.529163
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.