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human VPREB3 shRNA silencing AAV

Name 
AAV-h-VPREB3-shRNA
Cat No 
shAAV-227512
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human VPREB3.

shAAV-227512
AAV-h-VPREB3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VPREB3 (pre-B lymphocyte 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
8HS20; N27C7-2
Description (Vector)
VPREB3 is the human homolog of the mouse VpreB3 (8HS20) protein, and is specifically expressed in cell lines representative of all stages of B-cell differentiation. It is also related to VPREB1 and other members of the immunoglobulin supergene family. This protein associates with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. The precise function of the protein is not known, but it may contribute to mu chain transport in pre-B cells.
Gene ID
29802
Gene Name (Vector)
pre-B lymphocyte 3
Gene Symbol
VPREB3
HGNC ID
HGNC:12710
ORF Size (aa)
372
RefSeq ID
NM_013378
RefSeq Synonyms
NM_013378, BC020666,
Species
human
UniGene ID
Hs.136713

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.