human VGF shRNA silencing AAV

Name
AAV-h-VGF-shRNA

Cat No
shAAV-227466

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human VGF.

shAAV-227466

AAV-h-VGF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VGF (VGF nerve growth factor inducible). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SCG7; SgVII

Description (Vector)

VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known.

Gene ID

7425

Gene Name (Vector)

VGF nerve growth factor inducible

Gene Symbol

VGF

HGNC ID

HGNC:12684

ORF Size (aa)

1848

ORF Size (bp)

1848 bp

RefSeq ID

NM_003378

RefSeq Synonyms

NM_003378, BC063835, BC044212,

Species

human

UniGene ID

Hs.718797

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.