human VCAM1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human VCAM1.
shAAV-227422
AAV-h-VCAM1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human VCAM1 (vascular cell adhesion molecule 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD106; INCAM-100
Description (Vector)
VCAM1 is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Gene ID
7412
Gene Name (Vector)
vascular cell adhesion molecule 1
Gene Symbol
VCAM1
HGNC ID
HGNC:12663
ORF Size (aa)
2220
ORF Size (bp)
2220 bp
RefSeq ID
NM_001078
RefSeq Synonyms
NM_080682, NM_001199834, NM_001078, BC085003, BC068490, BC017276,
Species
human
UniGene ID
Hs.109225
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.