human VAMP7 shRNA silencing AAV

Name 
AAV-h-VAMP7-shRNA
Cat No 
shAAV-227389
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human VAMP7.

shAAV-227389
AAV-h-VAMP7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human VAMP7 (vesicle associated membrane protein 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SYBL1; synaptobrevin-like 1; synaptobrevin-like protein 1; tetanus neurotoxin-insensitive VAMP; tetanus-insensitive VAMP; TIVAMP; TI-VAMP; VAMP-7; vesicle-associated membrane protein 7
Description (eCommerce)
Vesicle-associated membrane protein 7 (VAMP7) is a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. VAMP7 localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes [taken from NCBI Entrez Gene (Gene ID: 6845)].
Description (Vector)
VAMP7 encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.
Gene ID
6845
Gene Name (eCommerce)
vesicle associated membrane protein 7
Gene Name (Vector)
vesicle associated membrane protein 7
Gene Symbol
VAMP7
HGNC ID
HGNC:11486
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
663
Protein Name (eCommerce)
Vesicle-associated membrane protein 7
RefSeq ID
NM_005638
RefSeq Synonyms
NM_005638, NM_001185183, NM_001145149, BC056141,
Research Areas
Golgi Apparatus,Immunology,Lysosomal Transport,Lysosome,Neurobiology,Synapse,Transport
Research Areas (Faceted)
cell_biology,immunology,neurobiology
Species
human
Target Sentence
Vesicle-associated membrane protein 7 (VAMP7) is a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. VAMP7 localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes [taken from NCBI Entrez Gene (Gene ID: 6845)].
UniGene ID
Hs.24167
UniProt ID (eCommerce)
P51809

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.