human UTS2 shRNA silencing AAV

Name
AAV-h-UTS2-shRNA

Cat No
shAAV-227368

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human UTS2.

shAAV-227368

AAV-h-UTS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UTS2 (urotensin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PRO1068; U-II; UCN2; UII

Description (Vector)

UTS2 encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene.

Gene ID

10911

Gene Name (Vector)

urotensin 2

Gene Symbol

UTS2

HGNC ID

HGNC:12636

ORF Size (aa)

285

RefSeq ID

NM_006786

RefSeq Synonyms

NM_021995, NM_006786, BC126443,

Species

human

UniGene ID

Hs.715862

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.