human USP7 shRNA silencing AAV

Name 
AAV-h-USP7-shRNA
Cat No 
shAAV-227346
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human USP7.

shAAV-227346
AAV-h-USP7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human USP7 (ubiquitin specific peptidase 7). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
deubiquitinating enzyme 7; HAUSP; Herpes virus-associated ubiquitin-specific protease; Herpesvirus-associated ubiquitin-specific protease; TEF1; ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin-specific-processing protease 7; USP7
Description (eCommerce)
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 7 (USP7) is a member of this family that has been shown to interact and stabilize p53.
Gene ID
7874
Gene Name (eCommerce)
ubiquitin specific peptidase 7
Gene Name (Vector)
ubiquitin specific peptidase 7
Gene Symbol
USP7
HGNC ID
HGNC:12630
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3309
ORF Size (bp)
3309 bp
Protein Name (eCommerce)
Ubiquitin carboxyl-terminal hydrolase 7
RefSeq ID
NM_003470
RefSeq Synonyms
NM_003470, NM_001321858, NM_001286458, NM_001286457, BC166690,
Research Areas
Apoptosis,Cancer,DNA Damage/Repair,FoxO Signaling,Host-Virus Interactions,p53 Signaling,RNA Processing,Signal Transduction,Toll-like Receptor Signaling,Transcription Factor/Regulator,Ubiquitination,Viral Carcinogenesis
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,genetics,transcription_translation,signal_transduction,infectious_disease,signal_transduction,genetics,transcription_translation,signal_transduction,immunology,genetics,transcription_translation,cancer,infectious_disease
Species
human
Target Sentence
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 7 (USP7) is a member of this family that has been shown to interact and stabilize p53.
UniGene ID
Hs.706830
UniProt ID (eCommerce)
Q93009

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.