human USP46 shRNA silencing AAV

Name 
AAV-h-USP46-shRNA
Cat No 
shAAV-227332
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human USP46.

shAAV-227332
AAV-h-USP46-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human USP46 (ubiquitin specific peptidase 46). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 (PubMed 14715245)).(supplied by OMIM, Jun 2009)
Gene ID
64854
Gene Name (Vector)
ubiquitin specific peptidase 46
Gene Symbol
USP46
HGNC ID
HGNC:20075
ORF Size (aa)
1101
ORF Size (bp)
1101 bp
RefSeq ID
NM_022832
RefSeq Synonyms
NM_022832, NM_001286768, NM_001286767, NM_001134223, BC037574,
Species
human
UniGene ID
Hs.7966

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.