human USH1C shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human USH1C.
shAAV-227271
AAV-h-USH1C-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human USH1C (USH1 protein network component harmonin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AIE-75; DFNB18; DFNB18A; NY-CO-37; NY-CO-38; PDZ-45; PDZ-73; PDZ-73/NY-CO-38; PDZ73; PDZD7C; ush1cpst
Description (Vector)
USH1C encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
10083
Gene Name (Vector)
USH1 protein network component harmonin
Gene Symbol
USH1C
HGNC ID
HGNC:12597
ORF Size (aa)
1602
ORF Size (bp)
1602 bp
RefSeq ID
NM_005709
RefSeq Synonyms
NM_153676, NM_005709, NM_001297764, BC016057,
Species
human
UniGene ID
Hs.502072
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.