human TXNRD2 shRNA silencing AAV

Name 
AAV-h-TXNRD2-shRNA
Cat No 
shAAV-226931
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TXNRD2.

shAAV-226931
AAV-h-TXNRD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TXNRD2 (thioredoxin reductase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SELZ; TR; TR-BETA; TR3; TRXR2
Description (Vector)
Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22.
Gene ID
10587
Gene Name (Vector)
thioredoxin reductase 2
Gene Symbol
TXNRD2
HGNC ID
HGNC:18155
ORF Size (aa)
1479
ORF Size (bp)
1479 bp
RefSeq ID
NM_006440
RefSeq Synonyms
NM_006440, NM_001282512, BC117354, BC099923,
Species
human
UniGene ID
Hs.443430

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.