human TUBG1 shRNA silencing AAV

Name
AAV-h-TUBG1-shRNA

Cat No
shAAV-226842

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TUBG1.

shAAV-226842

AAV-h-TUBG1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TUBG1 (tubulin gamma 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CDCBM4; Gamma-1-tubulin; gamma-tubulin complex component 1; GCP-1; TUBG; TUBGCP1; tubulin gamma-1 chain; tubulin, gamma polypeptide

Description (eCommerce)

Gamma tubulin is a member of the tubulin superfamily. Gamma tubulin localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle [taken from NCBI Entrez Gene (GeneID: 7283)].

Description (Vector)

TUBG1 encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.

Gene ID

7283

Gene Name (eCommerce)

tubulin gamma 1

Gene Name (Vector)

tubulin gamma 1

Gene Symbol

TUBG1

HGNC ID

HGNC:12417

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1356

ORF Size (bp)

1356 bp

Protein Name (eCommerce)

Tubulin gamma-1 chain

RefSeq ID

NM_001070

RefSeq Synonyms

NM_001070, BC000619,

Research Areas

Cell Cycle,Cytoskeleton,PLK1 Signaling,Signal Transduction

Research Areas (Faceted)

cell_biology,cell_cycle,genetics,signal_transduction

Species

human

Target Sentence

Gamma tubulin is a member of the tubulin superfamily. Gamma tubulin localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle [taken from NCBI Entrez Gene (GeneID: 7283)].

UniGene ID

Hs.279669

UniProt ID (eCommerce)

P23258

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.