human TSPO shRNA silencing AAV

Name
AAV-h-TSPO-shRNA

Cat No
shAAV-226654

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TSPO.

shAAV-226654

AAV-h-TSPO-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TSPO (translocator protein (18kDa)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BPBS; BZRP; DBI; IBP; MBR; mDRC; PBR; PBS; pk18; PKBS; PTBR;

Description (Vector)

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.

Gene ID

706

Gene Name (Vector)

translocator protein (18kDa)

Gene Symbol

TSPO

HGNC ID

HGNC:1158

ORF Size (aa)

510

RefSeq ID

NM_000714

RefSeq Synonyms

NM_007311, NM_001256531, NM_001256530, NM_000714, BC001110,

Species

human

UniGene ID

Hs.202

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.