human TSPAN32 shRNA silencing AAV

Name
AAV-h-TSPAN32-shRNA

Cat No
shAAV-226644

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TSPAN32.

shAAV-226644

AAV-h-TSPAN32-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TSPAN32 (tetraspanin 32). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ART1; PHEMX; PHMX; TSSC6

Description (Vector)

This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene ID

10077

Gene Name (Vector)

tetraspanin 32

Gene Symbol

TSPAN32

HGNC ID

HGNC:13410

ORF Size (aa)

777

RefSeq ID

NM_139022

RefSeq Synonyms

NM_139022, BC016693,

Species

human

UniGene ID

Hs.271954

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.