human TSLP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TSLP.
shAAV-226613
AAV-h-TSLP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TSLP (thymic stromal lymphopoietin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
TSLP encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
Gene ID
85480
Gene Name (Vector)
thymic stromal lymphopoietin
Gene Symbol
TSLP
HGNC ID
HGNC:30743
ORF Size (aa)
480
RefSeq ID
NM_033035
RefSeq Synonyms
NM_138551, NM_033035, BC040592,
Species
human
UniGene ID
Hs.389874
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.