human TSC22D4 shRNA silencing AAV

Name 
AAV-h-TSC22D4-shRNA
Cat No 
shAAV-226587
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TSC22D4.

shAAV-226587
AAV-h-TSC22D4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TSC22D4 (TSC22 domain family member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
66
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
THG1; THG-1; TILZ2; TSC22 domain family protein 4; tsc-22-like protein THG-1; TSC22-related-inducible leucine zipper protein 2
Description (eCommerce)
TSC22 domain family member 4 (TSC22D4) is a member of the TSC22 (TGF-beta-1-stimulated clone 22) domain family of leucine zipper transcription factors. In mice, TSC22D4, also known as Thg-1pit, is involved in the induction of cerebella granule neuron apoptosis and may a play a role in neuron development and differentiation.
Description (Vector)
TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators (see TSC22D3; MIM 300506) (Kester et al., 1999 (PubMed 10488076); Fiorenza et al., 2001 (PubMed 11707329)).(supplied by OMIM, Mar 2008)
Gene ID
81628
Gene Name (eCommerce)
TSC22 domain family member 4
Gene Name (Vector)
TSC22 domain family member 4
Gene Symbol
TSC22D4
HGNC ID
HGNC:21696
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
933
Protein Name (eCommerce)
TSC22 domain family protein 4
RefSeq ID
NM_030935
RefSeq Synonyms
NM_030935, NM_001303043, BC031622, BC010406, BC002972, BC001966, BC001486,
Research Areas
Neurobiology,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,neurobiology,transcription_translation
Species
human
Target Sentence
TSC22 domain family member 4 (TSC22D4) is a member of the TSC22 (TGF-beta-1-stimulated clone 22) domain family of leucine zipper transcription factors. In mice, TSC22D4, also known as Thg-1pit, is involved in the induction of cerebella granule neuron apoptosis and may a play a role in neuron development and differentiation.
UniGene ID
Hs.469798
UniProt ID (eCommerce)
Q9Y3Q8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.