human TSC22D3 shRNA silencing AAV

Name 
AAV-h-TSC22D3-shRNA
Cat No 
shAAV-226582
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TSC22D3.

shAAV-226582
AAV-h-TSC22D3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TSC22D3 (TSC22 domain family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DIP; DSIPI; GILZ; TSC-22R
Description (Vector)
TSC22D3 shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine. Transcript variants encoding different isoforms have been identified for this gene.
Gene ID
1831
Gene Name (Vector)
TSC22 domain family member 3
Gene Symbol
TSC22D3
HGNC ID
HGNC:3051
ORF Size (aa)
405
RefSeq ID
NM_004089
RefSeq Synonyms
NM_198057, NM_004089, NM_001318470, NM_001318468, NM_001015881, BC072446, BC018148,
Species
human
UniGene ID
Hs.716410

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.