human TROVE2 shRNA silencing AAV

Name
AAV-h-TROVE2-shRNA

Cat No
shAAV-226533

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TROVE2.

shAAV-226533

AAV-h-TROVE2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TROVE2 (TROVE domain family member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

60 kDa ribonucleoprotein Ro; 60 kDa Ro protein; 60 kDa SS-A/Ro ribonucleoprotein; gastric cancer multi-drug resistance protein; Ro 60 kDa autoantigen; RO60; RORNP; Sjoegren syndrome antigen A2; sjoegren syndrome type A antigen; Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-A/Ro); SS-A; SSA2; TROVE domain family member 2

Description (eCommerce)

Ro60 is a RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. Ro60 may stabilize these RNAs from degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P10155].

Gene ID

6738

Gene Name (eCommerce)

TROVE domain family member 2

Gene Name (Vector)

TROVE domain family member 2

Gene Symbol

TROVE2

HGNC ID

HGNC:11313

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1617

ORF Size (bp)

1617 bp

Protein Name (eCommerce)

60 kDa SS-A/Ro ribonucleoprotein

RefSeq ID

NM_004600

RefSeq Synonyms

NM_004600, NM_001331020, NM_001173525, NM_001173524, NM_001042370, NM_001042369, BC036658,

Research Areas

RNA Binding,RNA Processing,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

Ro60 is a RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. Ro60 may stabilize these RNAs from degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P10155].

UniGene ID

Hs.288178

UniProt ID (eCommerce)

P10155

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.