human TRIP4 shRNA silencing AAV

Name 
AAV-h-TRIP4-shRNA
Cat No 
shAAV-226501
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TRIP4.

shAAV-226501
AAV-h-TRIP4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRIP4 (thyroid hormone receptor interactor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
activating signal cointegrator 1; ASC1; ASC-1; HsT17391; MDCDC; SMABF1; thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; ZC2HC5; zinc finger, C2HC5-type
Description (eCommerce)
Thyroid receptor interacting protein 4 (TRIP4) is also known as activating signal cointegrator 1 (ASC-1). TRIP4/ASC-1 was identified as a protein that interacts with the thyroid receptor. It has been shown to act as a transcriptional co-activator of the thyroid receptor (TR), 9-cis retinoic acid (RXR), androgen receptor (AR) and estrogen.
Gene ID
9325
Gene Name (eCommerce)
thyroid hormone receptor interactor 4
Gene Name (Vector)
thyroid hormone receptor interactor 4
Gene Symbol
TRIP4
HGNC ID
HGNC:12310
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1746
ORF Size (bp)
1746 bp
Protein Name (eCommerce)
Activating signal cointegrator 1
RefSeq ID
NM_016213
RefSeq Synonyms
NM_016213, NM_001321924, BC012448,
Research Areas
Cytoskeleton,Nuclear Receptor Coactivators,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Thyroid receptor interacting protein 4 (TRIP4) is also known as activating signal cointegrator 1 (ASC-1). TRIP4/ASC-1 was identified as a protein that interacts with the thyroid receptor. It has been shown to act as a transcriptional co-activator of the thyroid receptor (TR), 9-cis retinoic acid (RXR), androgen receptor (AR) and estrogen.
UniGene ID
Hs.500340
UniProt ID (eCommerce)
Q15650

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.