human TRIM10 shRNA silencing AAV

Name
AAV-h-TRIM10-shRNA

Cat No
shAAV-226395

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TRIM10.

shAAV-226395

AAV-h-TRIM10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRIM10 (tripartite motif containing 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HERF1; RFB30; RNF9

Description (Vector)

TRIM10 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic bodies. Studies in mice suggest that this protein plays a role in terminal differentiation of erythroid cells. Alternate splicing of this gene generates two transcript variants encoding different isoforms.

Gene ID

10107

Gene Name (Vector)

tripartite motif containing 10

Gene Symbol

TRIM10

HGNC ID

HGNC:10072

ORF Size (aa)

1188

RefSeq ID

NM_006778

RefSeq Synonyms

NM_052828, NM_006778, BC113419, BC093926,

Species

human

UniGene ID

Hs.709483

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.