human TPH1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TPH1.
shAAV-226256
AAV-h-TPH1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TPH1 (tryptophan hydroxylase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TPRH; TRPH
Description (Vector)
TPH1 encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
Gene ID
7166
Gene Name (Vector)
tryptophan hydroxylase 1
Gene Symbol
TPH1
HGNC ID
HGNC:12008
ORF Size (aa)
1335
ORF Size (bp)
1335 bp
RefSeq ID
NM_004179
RefSeq Synonyms
NM_004179, BC106739,
Species
human
UniGene ID
Hs.591999
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.