human TOR1A shRNA silencing AAV

Name 
AAV-h-TOR1A-shRNA
Cat No 
shAAV-226211
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TOR1A.

shAAV-226211
AAV-h-TOR1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TOR1A (torsin family 1 member A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DQ2; DYT1
Description (Vector)
TOR1A is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1.
Gene ID
1861
Gene Name (Vector)
torsin family 1 member A
Gene Symbol
TOR1A
HGNC ID
HGNC:3098
ORF Size (aa)
999
RefSeq ID
NM_000113
RefSeq Synonyms
NM_000113, BC014484, BC000674,
Species
human
UniGene ID
Hs.534312

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.