human TNPO1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TNPO1.
shAAV-226150
AAV-h-TNPO1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TNPO1 (transportin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IPO2; KPNB2; MIP; MIP1; TRN
Description (Vector)
TNPO1 encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.
Gene ID
3842
Gene Name (Vector)
transportin 1
Gene Symbol
TNPO1
HGNC ID
HGNC:6401
ORF Size (aa)
2673
ORF Size (bp)
2673 bp
RefSeq ID
NM_002270
RefSeq Synonyms
NM_153188, NM_002270, BC040340,
Species
human
UniGene ID
Hs.482497
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.