human TMPRSS4 shRNA silencing AAV

Name
AAV-h-TMPRSS4-shRNA

Cat No
shAAV-226016

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TMPRSS4.

shAAV-226016

AAV-h-TMPRSS4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TMPRSS4 (transmembrane protease, serine 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CAPH2; MT-SP2; TMPRSS3

Description (Vector)

TMPRSS4 encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. TMPRSS4 was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

56649

Gene Name (Vector)

transmembrane protease, serine 4

Gene Symbol

TMPRSS4

HGNC ID

HGNC:11878

ORF Size (aa)

1314

ORF Size (bp)

1314 bp

RefSeq ID

NM_019894

RefSeq Synonyms

NM_019894, NM_001290096, NM_001290094, NM_001173552, NM_001173551, NM_001083947, BC011703, BC004855,

Species

human

UniGene ID

Hs.161985

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.