human TMLHE shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TMLHE.
shAAV-225996
AAV-h-TMLHE-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TMLHE (trimethyllysine hydroxylase, epsilon). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AUTSX6; BBOX2; TMLD; TMLH; TMLHED; XAP130
Description (Vector)
TMLHE encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.
Gene ID
55217
Gene Name (Vector)
trimethyllysine hydroxylase, epsilon
Gene Symbol
TMLHE
HGNC ID
HGNC:18308
ORF Size (aa)
1131
RefSeq ID
NM_018196
RefSeq Synonyms
NM_018196, NM_001184797, BC025269,
Species
human
UniGene ID
Hs.133321
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.