human UBE2V1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human UBE2V1.
shAAV-225826
AAV-h-UBE2V1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human UBE2V1 (ubiquitin conjugating enzyme E2 V1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CIR1; CROC-1; CROC1; UBE2V; UEV-1; UEV1; UEV1A
Description (Vector)
Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Gene ID
7335
Gene Name (Vector)
ubiquitin conjugating enzyme E2 V1
Gene Symbol
UBE2V1
HGNC ID
HGNC:12494
ORF Size (aa)
444
RefSeq ID
NM_021988
RefSeq Synonyms
NM_199144, NM_022442, NM_021988, NM_001282580, NM_001282579, NM_001282578, NM_001282577, NM_001282576, NM_001282575, NM_001257399, NM_001257398, NM_001257397, NM_001257396, NM_001257395, NM_001257394, NM_001257393, NM_001032288, BC000468,
Species
human
UniGene ID
Hs.420529
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.