human TM2D1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TM2D1.
shAAV-225604
AAV-h-TM2D1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TM2D1 (TM2 domain containing 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BBP
Description (Vector)
TM2D1 is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death.
Gene ID
83941
Gene Name (Vector)
TM2 domain containing 1
Gene Symbol
TM2D1
HGNC ID
HGNC:24142
ORF Size (aa)
624
RefSeq ID
NM_032027
RefSeq Synonyms
NM_032027, BC029486,
Species
human
UniGene ID
Hs.656790
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.