human TGS1 shRNA silencing AAV

Name
AAV-h-TGS1-shRNA

Cat No
shAAV-225412

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TGS1.

shAAV-225412

AAV-h-TGS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TGS1 (trimethylguanosine synthase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

cap-specific guanine-N2 methyltransferase; CLL-associated antigen KW-2; hepatocellular carcinoma-associated antigen 137; NCOA6IP; nuclear receptor coactivator 6-interacting protein; PIMT; PIPMT; PRIP-interacting protein with methyltransferase motif; trimethylguanosine synthase

Description (eCommerce)

PIMT, also known as TGS1, was originally identified in yeast as a protein involved in RNA cap trimethylation and the transfer of methyl from S-adenosylmethionine to m7GTP and m7GDP.

Gene ID

96764

Gene Name (eCommerce)

trimethylguanosine synthase 1

Gene Name (Vector)

trimethylguanosine synthase 1

Gene Symbol

TGS1

HGNC ID

HGNC:17843

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2562

ORF Size (bp)

2562 bp

Protein Name (eCommerce)

Trimethylguanosine synthase

RefSeq ID

NM_024831

RefSeq Synonyms

NM_024831, NM_001317902, BC160105, BC011999,

Research Areas

Gene Expression,Metabolism/Metabolic Process,Methyltransferase,RNA Processing,RNA Transport,Spliceosome,Transcription Factor/Regulator

Research Areas (Faceted)

genetics,transcription_translation,metabolism,cell_biology

Species

human

Target Sentence

PIMT, also known as TGS1, was originally identified in yeast as a protein involved in RNA cap trimethylation and the transfer of methyl from S-adenosylmethionine to m7GTP and m7GDP.

UniGene ID

Hs.335068

UniProt ID (eCommerce)

Q96RS0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.