human TGM6 shRNA silencing AAV

Name 
AAV-h-TGM6-shRNA
Cat No 
shAAV-225407
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TGM6.

shAAV-225407
AAV-h-TGM6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TGM6 (transglutaminase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
dJ734P14.3; SCA35; TG6; TGM3L; TGY
Description (Vector)
TGM6 belongs to the transglutaminase superfamily. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Mutations in this gene are associated with spinocerebellar ataxia type 35 (SCA35). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
343641
Gene Name (Vector)
transglutaminase 6
Gene Symbol
TGM6
HGNC ID
HGNC:16255
ORF Size (aa)
2121
ORF Size (bp)
2121 bp
RefSeq ID
NM_198994
RefSeq Synonyms
NM_198994, NM_001254734, BC166680,
Species
human
UniGene ID
Hs.452039

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.