human TGM3 shRNA silencing AAV

Name
AAV-h-TGM3-shRNA

Cat No
shAAV-225402

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TGM3.

shAAV-225402

AAV-h-TGM3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TGM3 (transglutaminase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

TGE

Description (Vector)

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.

Gene ID

7053

Gene Name (Vector)

transglutaminase 3

Gene Symbol

TGM3

HGNC ID

HGNC:11779

ORF Size (aa)

2082

ORF Size (bp)

2082 bp

RefSeq ID

NM_003245

RefSeq Synonyms

NM_003245, BC109076, BC109075,

Species

human

UniGene ID

Hs.2022

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.