human TFAP2B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TFAP2B.
shAAV-225345
AAV-h-TFAP2B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TFAP2B (transcription factor AP-2 beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AP-2B; AP2-B; PDA2
Description (Vector)
TFAP2B encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
Gene ID
7021
Gene Name (Vector)
transcription factor AP-2 beta
Gene Symbol
TFAP2B
HGNC ID
HGNC:11743
ORF Size (aa)
1383
ORF Size (bp)
1383 bp
RefSeq ID
NM_003221
RefSeq Synonyms
NM_003221, BC037225,
Species
human
UniGene ID
Hs.33102
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.