human TERF2 shRNA silencing AAV

Cat. No: shAAV-225307

Availability: 4-5 weeks

Name: AAV-h-TERF2-shRNA

This is an AAV expressing shRNA for silencing of Human TERF2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TERF2
Gene Name: telomeric repeat binding factor 2
Gene ID: 7014
Gene Synonyms: TRBF2; TRF2
ORF Size: 756 bp
RefSeq#: NM_005652
Gene Description: TERF2 encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
UniGene ID: Hs.63335
HGNC ID: HGNC:11729