human TERF1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TERF1.
shAAV-225306
AAV-h-TERF1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TERF1 (telomeric repeat binding factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hTRF1-AS; PIN2; t-TRF1; TRBF1; TRF; TRF1
Description (Vector)
TERF1 encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
Gene ID
7013
Gene Name (Vector)
telomeric repeat binding factor 1
Gene Symbol
TERF1
HGNC ID
HGNC:11728
ORF Size (aa)
1260
ORF Size (bp)
1260 bp
RefSeq ID
NM_017489
RefSeq Synonyms
NM_017489, NM_003218, BC029378,
Species
human
UniGene ID
Hs.442707
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.