human TCF7L2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TCF7L2.
shAAV-225221
AAV-h-TCF7L2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TCF7L2 (transcription factor 7 like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TCF-4; TCF4
Description (Vector)
TCF7L2 encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.
Gene ID
6934
Gene Name (Vector)
transcription factor 7 like 2
Gene Symbol
TCF7L2
HGNC ID
HGNC:11641
ORF Size (aa)
1368
ORF Size (bp)
1368 bp
RefSeq ID
NM_030756
RefSeq Synonyms
NM_030756, NM_001198531, NM_001198530, NM_001198529, NM_001198528, NM_001198527, NM_001198526, NM_001198525, NM_001146286, NM_001146285, NM_001146284, NM_001146283, NM_001146274, BC032656,
Species
human
UniGene ID
Hs.593995
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.